Searchable abstracts of presentations at key conferences in endocrinology

ea0029p2 | Adrenal cortex | ICEECE2012

Pathophysiological significance of CYP11B2 immunohistochemical staining in primary aldosteronism

Nanba K. , Tsuiki M. , Sawai K. , Mukai K. , Nakao K. , Tamanaha T. , Usui T. , Tagami T. , Okuno H. , Yamamoto T. , Shimatsu A. , Naruse M.

Background: Although primary aldosteronism (PA) is the common cause of hypertension subjected to surgery, methods of pathological confirmation of aldosterone overproduction have not been established. Aim of the study was to investigate immunohistochemically the expression of CYP11B2 in the adrenal tissue of PA.Methods: Twenty five patients with PA including 20 patients with aldosterone-producing adenoma (APA) and 5 patients without APA (non-APA) were stu...